United Kingdom Profile Updated
The United Kingdom profile in ClinRegs has been reviewed and updated with the following information:
- Revised Medicines and Healthcare Products Regulatory Agency (MHRA) fee schedule for clinical trials (See Regulatory Fees)
- Reference to new IRAS combined review user guide (See Scope of Assessment and Submission Process)
- Details about commercial model agreements being revised to align with the Commercial Chief Investigator Agreement (See Initiation, Agreements & Registration)
- Updated list of information covered in the General Data Protection Regulation (GDPR) transparency template to include definitions (See Personal Data Protection)
Sources Added During this Update:
(Guidance) IRAS User Guide (IRAS-User) (Current as of February 18, 2026)
Health Research Authority
(Article) Further Updates to the Commercial Agreements for Participating NHS and HSC Organisations (GBR-42) (Last Updated July 30, 2025)
Health Research Authority
Sources Revised During this Update:
(Guidance) Statutory Guidance: Current MHRA Fees (G-MHRAFees) (Updated January 12, 2026)
Medicines and Healthcare Products Regulatory Agency
(Guidance) Step-by-step Guide to Using IRAS for Combined Review (G-IRASCombRev) (Last Updated October 31, 2025)
Health Research Authority
(Webpage) GDPR Transparency Wording for all Sponsors (GBR-53) (Last Updated October 20, 2025)
Health Research Authority